%0 Journal Article
%T Placebo effect of acupuncture on insomnia: a systematic review and meta-analysis
%A Liu, Chengyong
%A Xi, Hanqing
%A Wu, Wenzhong
%A Wang, Xiaoqiu
%A Qin, Shan
%A Zhao, Yanan
%A Zheng, Shiyu
%A Wan, Qingyun
%A Xu, Liang
%J Annals of Palliative Medicine
%D 2020
%B 2020
%9 
%! Placebo effect of acupuncture on insomnia: a systematic review and meta-analysis
%K 
%X  Background:  Acupuncture is a common alternative therapy for clinical treatment of insomnia. As the underlying mechanism is yet unclear, its efficacy is often considered as placebo effect. To clarify whether acupuncture treatment of insomnia is only due to its placebo effect, a systematic review and a meta-analysis were designed based on the comparison between acupuncture and sham acupuncture.   Methods:  Four English (PubMed, Embase, Web of Science, and The Cochrane Library) and three Chinese (CNKI, VIP, and Wanfang) databases were searched, and the validity of the eligible studies was critically appraised. Thirteen eligible randomized controlled trials of moderate-to-high quality that employed polysomnography (PSG), actigraphy, or self-assessment sleep quality tools were included in the present study. A meta-analysis was conducted using a random-effects model with the Pittsburgh Sleep Quality Index (PSQI) as the primary outcome measure (911 adult patients, 13 trials) for trials investigating the effects of acupuncture as compared to the sham acupuncture. Then, a subgroup analysis was performed to detect the sources of heterogeneity, identify the selection of sham acupuncture methods and different crowd characteristics, and explore its contributions to the total score change of PSQI.   Results:  Compared to the sham groups, acupuncture significantly decreased the PSQI score (P Conclusions:  Acupuncture treatment of insomnia is efficacious, not because of its placebo effect. For the selection of sham acupuncture, both methods performed similarly in a clinical setting. Moreover, insomnia patients with major depression disorder were not recommended to use only acupuncture treatment.
%U https://apm.amegroups.org/article/view/34506
%V 9
%N 1
%P 19-29
%@ 2224-5839