TY - JOUR AU - Benjamin Cheng, Hon Wai AU - Chan, Kwok Ying AU - Judy Chung, Yuen Kwan AU - Choi, Chun Wai AU - Chan, Chun Hung AU - Ching Cheng, Shuk AU - Chan, Wan Hung AU - Fung, Koon Sim AU - Wong, Kar Yin AU - Iman Chan, Oi Man AU - Wah Man, Ching PY - 2017 TI - Supportive & palliative interventions in motor neurone disease: what we know from current literature? JF - Annals of Palliative Medicine; Vol 7, No 3 (July 19, 2018): Annals of Palliative Medicine (Neurology Palliative Care Service: Development & Clinical Outcomes) Y2 - 2017 KW - N2 - Although there is no cure for motor neurone disease (MND), the advent of supportive interventions including multidisciplinary care (MDC) has improved treatment interventions and enhanced quality of life (QOL) for MND patients and their carers. Our integrative review showed evidence-based MDC, respiratory management and disease-modifying therapy that have improved the outcomes of patients diagnosed with MND. Supportive approaches to nutritional maintenance and optimization of symptomatic treatments, including management of communication and neuropsychiatric issues, improve the QOL for MND patients. Notwithstanding improvement to care and QOL, survival benefit has become evident with the advent of a MDC framework, early treatment with non-invasive ventilation (NIV). In addition, weight maintenance remains critical, as weight loss is associated with more rapid disease progression. The endof- life phase is poorly defined in MND patients and treatment remains challenging, yet effective symptom control through palliative care (PC) is achievable and essential. UR - https://apm.amegroups.org/article/view/17160